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Repurposing clinical drugs is a promising strategy to discover drugs against Zika virus infection
Weibao Song, Hongjuan Zhang, Yu Zhang, Rui Li, Yanxing Han, Yuan Lin, Jiandong Jiang
Frontiers of Medicine 2021, Volume 15, Issue 3, Pages 404-415 doi: 10.1007/s11684-021-0834-9
Keywords: Zika virus clinical drugs ZIKV inhibitors antivirals repurposing
Development Strategy of Integrative Pharmacy
Zhang Yong, Zhao Yixiu, Yang Baofeng
Strategic Study of CAE 2021, Volume 23, Issue 1, Pages 185-192 doi: 10.15302/J-SSCAE-2021.01.022
Keywords: integrative pharmacy integrative drugs new drug development drug evaluation clinical medication guidance
Small-molecule anti-COVID-19 drugs and a focus on China’s homegrown mindeudesivir (VV116)
Frontiers of Medicine doi: 10.1007/s11684-023-1037-3
Keywords: COVID-19 antiviral drugs mindeudesivir
Peng Hu, Changsheng Guo, Yan Zhang, Jiapei Lv, Yuan Zhang, Jian Xu
Frontiers of Environmental Science & Engineering 2019, Volume 13, Issue 4, doi: 10.1007/s11783-019-1140-5
We developed a method for determining 11 abused drugs in water and METH and EPH were the dominant drugs in water Abuse drugs in Beiyunhe River were mainly from Abused drugs in the water would not impair the
Keywords: Drugs of abuse Occurrence Distribution Urban river Environmental risk
Chinese expert consensus on oral drugs for the treatment of mature B-cell lymphomas (2020 edition)
Frontiers of Medicine 2022, Volume 16, Issue 5, Pages 815-826 doi: 10.1007/s11684-021-0891-0
Keywords: B-cell lymphoma oral drug targeted therapy immunotherapy COVID-19 pandemic
Vaibhav Mundra, Ram I. Mahato
Frontiers of Chemical Science and Engineering 2014, Volume 8, Issue 4, Pages 387-404 doi: 10.1007/s11705-014-1457-3
Keywords: nanocarrier cellular uptake endosomal release nucleic acid drug
Telomeric impact of conventional chemotherapy
Yiming Lu, Waiian Leong, Olivier Guérin, Eric Gilson, Jing Ye
Frontiers of Medicine 2013, Volume 7, Issue 4, Pages 411-417 doi: 10.1007/s11684-013-0293-z
Keywords: telomere antineoplasic drugs conventional chemotherapies
LI Zhengming
Strategic Study of CAE 2000, Volume 2, Issue 7, Pages 92-93
Frontiers of Environmental Science & Engineering 2022, Volume 16, Issue 7, doi: 10.1007/s11783-021-1501-8
• Oxidation of methotrexate by high-valent metal-oxo species was first explored.
Keywords: Anticancer drugs High-valent metal-oxo species Oxidation kinetics Reaction mechanisms Multi-endpoint
Marie-Germaine Bousser
Frontiers of Medicine 2012, Volume 6, Issue 1, Pages 22-34 doi: 10.1007/s11684-012-0178-6
Keywords: stroke prevention vascular risk factors cerebral infarction cerebral hemorrhage anti-thrombotic drugs
Ontological reconstruction of the clinical terminology of traditional Chinese medicine
Li Ma,Baoyan Liu,Qi Xie,Shusong Mao,Zhiwei Cui
Frontiers of Medicine 2014, Volume 8, Issue 3, Pages 358-361 doi: 10.1007/s11684-014-0348-9
This study proposes the ontological reconstruction of the current clinical terminology of traditionalof preliminary work related to the said reconstruction, including the ontology-based analysis of TCM clinicalWe conclude that the ontological reconstruction of TCM clinical terminology provides a proper translation
Keywords: ontology traditional Chinese medicine clinical terminology
Factors related to compliance with oral analgesic treatment of inpatients with chronic pain
Hong Zhu,Yuzhu Zheng,Hui Gao,Li Liu,Lie Yang
Frontiers of Medicine 2015, Volume 9, Issue 3, Pages 374-379 doi: 10.1007/s11684-015-0411-1
This study aimed to determine the relationship between the different factors of analgesic therapy and the compliance of chronic pain inpatients. We prospectively investigated 100 consecutive inpatients with non-cancer chronic pain who were hospitalized to receive oral analgesic treatment in the Pain Department of West China Hospital from May 2013 to October 2013. Patients who completed the treatment plan were recorded as good compliance, whereas patients who partly completed or even refused the treatment were recorded as moderate or non-compliance, respectively. A total of 73 (73.7%), 17 (17.1%), and 9 (9.2%) patients showed good, moderate, and non-compliance, respectively. Univariate analyses showed significantly better compliance among farmers, patients educated in college or above, with family income of<3000 CNY, and with severe or moderate pain than those employed and unemployed (P=0.02), patients educated below college (P=0.013), with family income of≥3000 CNY (P=0.025), and with mild pain (P<0.001), respectively. Logistic regression analysis showed that the family income of≥3000 CNY (OR: 2.50, 95%CI: 1.65–4.51, P=0.021) and mild pain (OR: 1.27, 95%CI: 1.03–3.31, P=0.016) were associated with moderate or non-compliance with oral analgesic treatment. In conclusion, the low compliance with oral treatment of analgesics was found in Chinese inpatients with chronic pain and compliance was negatively associated with family income and degree of pain of patients.
Keywords: chronic pain inpatient oral paregoric drugs compliance
Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 10, Pages 1503-1515 doi: 10.1007/s11705-022-2294-4
Keywords: insoluble drugs polymer inhibition crystallization crystal growth kinetics DFT calculations
Frontiers of Medicine 2023, Volume 17, Issue 3, Pages 527-533 doi: 10.1007/s11684-022-0967-5
Keywords: orthotopic heart transplant tricuspid regurgitation clinical impact biatrial heart transplantation
Obesity-related glomerulopathy: pathogenesis, pathologic, clinical characteristics and treatment
Tianhua Xu, Zitong Sheng, Li Yao
Frontiers of Medicine 2017, Volume 11, Issue 3, Pages 340-348 doi: 10.1007/s11684-017-0570-3
Keywords: obesity-related glomerulopathy pathogenesis pathologic clinical characteristics
Title Author Date Type Operation
Repurposing clinical drugs is a promising strategy to discover drugs against Zika virus infection
Weibao Song, Hongjuan Zhang, Yu Zhang, Rui Li, Yanxing Han, Yuan Lin, Jiandong Jiang
Journal Article
Small-molecule anti-COVID-19 drugs and a focus on China’s homegrown mindeudesivir (VV116)
Journal Article
Occurrence, distribution and risk assessment of abused drugs and their metabolites in a typical urban
Peng Hu, Changsheng Guo, Yan Zhang, Jiapei Lv, Yuan Zhang, Jian Xu
Journal Article
Chinese expert consensus on oral drugs for the treatment of mature B-cell lymphomas (2020 edition)
Journal Article
nanocarriers for efficient cellular uptake and endosomal release of small molecule and nucleic acid drugs
Vaibhav Mundra, Ram I. Mahato
Journal Article
Telomeric impact of conventional chemotherapy
Yiming Lu, Waiian Leong, Olivier Guérin, Eric Gilson, Jing Ye
Journal Article
A Review of the International Workshop on “Technological Upgradation of Drugs/Pharmaceutical & Agrochemical
LI Zhengming
Journal Article
Product identification and toxicity change during oxidation of methotrexate by ferrate and permanganate in water
Journal Article
Ontological reconstruction of the clinical terminology of traditional Chinese medicine
Li Ma,Baoyan Liu,Qi Xie,Shusong Mao,Zhiwei Cui
Journal Article
Factors related to compliance with oral analgesic treatment of inpatients with chronic pain
Hong Zhu,Yuzhu Zheng,Hui Gao,Li Liu,Lie Yang
Journal Article
Theoretical insights into influence of additives on sulfamethoxazole crystal growth kinetics and mechanisms
Journal Article
The clinical impact of tricuspid regurgitation in patients with a biatrial orthotopic heart transplant
Journal Article